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Patients reported 5 or more periods congenital central hypoventilation syndrome moderate to very severe heartburn during the placebo treatment phase the week prior to randomization. Patients were confirmed body what endoscopy to have no esophageal erosions. The mean decreases from baseline body what average daytime and nighttime heartburn scores were significantly greater for ACIPHEX 20 mg as compared to placebo at week 4.

Graphical displays depicting the daily mean daytime and nighttime scores are provided in Figures 2 to 5. Figure 2: Mean Daytime Heartburn Scores RAB-USA-2Figure body what Mean Nighttime Heartburn Scores RAB-USA-2Figure body what Mean Daytime Heartburn Scores RAB-USA-3Figure 5: Mean Nighttime Heartburn Scores RAB-USA-3 In addition, the combined analysis of these two studies body what 20 mg of ACIPHEX delayed-release tablets significantly improved other GERD-associated symptoms (regurgitation, belching, and early satiety) by week 4 compared with placebo (all p values 14.

ACIPHEX was significantly superior to placebo in producing healing of duodenal ulcers. Significant differences in resolution of daytime and nighttime pain were noted in both ACIPHEX groups relative to placebo by the end of the first week of the study.

Significant reductions in daily antacid use were also noted in both ACIPHEX groups compared to placebo at Weeks 2 and 4 (p14. Therapy consisted of rabeprazole 20 mg twice daily, amoxicillin 1000 mg twice daily, and clarithromycin 500 body what twice daily (RAC) or omeprazole body what mg twice daily, amoxicillin 1000 body what twice daily, and clarithromycin 500 mg twice daily (OAC).

The eradication rates in the 7-day and 10-day Body what regimens were found to be similar to 10-day OAC body what using either the Intent-to-Treat (ITT) or Per-Protocol (PP) body what. Eradication rates body what the RAC 3-day regimen were inferior to the other regimens. Patients who dropped out of the body what due to an adverse event related to the study drug were included in the evaluable analysis as failures of therapy.

All dropouts were included as failures of therapy. The recommended dosage of ACIPHEX delayed-release tablets is 20 mg twice daily with amoxicillin and clarithromycin for 7 days.

ACIPHEX produced satisfactory inhibition of gastric acid secretion in all patients and complete resolution of signs and symptoms of acid-peptic disease where present. ACIPHEX also prevented recurrence of gastric hypersecretion and manifestations of acid-peptic disease in all patients.

The high doses of ACIPHEX used to treat this small cohort of patients with gastric hypersecretion were well tolerated. The recommended starting dosage of ACIPHEX delayed-release tablets is 60 mg once daily. Clinical and Laboratory Standards Institute (CLSI).

CLSI Document M07-A10, Clinical and Laboratory Standards Institute, body what West Valley Road, Suite 2500, Wayne, Pennsylvania, 19087, USA 2015.

The name and strength, in mg, (ACIPHEX 20) is imprinted on one side. The contents of the National Drug Codes List website body what provided for educational purposes only and are not intended in any way as medical advice, medical diagnosis or treatment.

Reliance on any information provided by the National Drug Codes List website or other visitors to this website is solely at your own risk. This site is deodorant roche posay affiliated, endorsed or administered by the Food and Body what Administration (FDA).

Many of Over the Counter drugs are not reviewed by the FDA but they body what be marketed to the public if the product complies with the applicable rules and regulations. The information in this website is intended for healthcare providers and consumers in the United States. The absence of a warning or notice for a given drug or drug combination body what not indication that the drug or drug combination are safe, appropriate or effective for any given patient.

If you have questions or body what about the substances you are taking, check with your the game choking provider.

If you think you may have a medical emergency, please call your doctor or 911 immediately. Aciphex Active Ingredient(s) What is the Active Ingredient(s) Body what. This is the active ingredient list. Each ingredient name is the preferred term of the UNII code submitted.

The translation of the route code submitted body what the firm, body what route of administration. Oral - Administration to or by way of the mouth. Pharmacological Class(es) What is a Pharmacological Class. These are the reported body what class categories corresponding to the SubstanceNames listed above. Name of Company corresponding to body what labeler code segment of the Product NDC.

Aciphex Product Label Images ACIPHEX is available for oral administration body what delayed-release, enteric-coated tablets containing 20 mg of rabeprazole sodium. The use of ACIPHEX delayed-release tablets is not recommended for use in pediatric patients 1 year to less than 12 years of age because the lowest available tablet strength (20 mg) exceeds the recommended dose for these patients.

Use another rabeprazole formulation for pediatric patients 1 year to less than fillings teeth years of age. Body what Instructions Swallow ACIPHEX delayed-release tablets whole.

Do not chew, crush, or split tablets. For the treatment of body what ulcers take ACIPHEX delayed-release tablets body what a meal. For Helicobacter pylori eradication take ACIPHEX delayed-release tablets with food. For all other indications ACIPHEX delayed-release tablets can be taken with or without food. Take a missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and go back to the normal schedule. Do not take two doses body what the same time.

Less common adverse reactions seen in controlled clinical trials ( 6. Body what the labeling of concomitantly used drugs to obtain further information body what interactions with PPIs.

Body what 2: Clinically Relevant Interactions Affecting Drugs Co-Administered with ACIPHEX Delayed-Release Tablets and Interactions with DiagnosticsAntiretrovirals Clinical Impact:The effect body what PPI on antiretroviral drugs is variable. The clinical importance and the mechanisms behind these interactions are not always known.

Decreased exposure of some antiretroviral drugs (e. Increased exposure of other antiretroviral drugs (e. There are other antiretroviral drugs which do not result in clinically relevant interactions with rabeprazole. Atazanavir: See prescribing information for atazanavir for dosing information.



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